Michał Nowicki Selected Research

Topotecan (Hycamtin)

5/2022	The Profile of MicroRNA Expression and Potential Role in the Regulation of Drug-Resistant Genes in Doxorubicin and Topotecan Resistant Ovarian Cancer Cell Lines.
3/2022	Effect of ALDH1A1 Gene Knockout on Drug Resistance in Paclitaxel and Topotecan Resistant Human Ovarian Cancer Cell Lines in 2D and 3D Model.
4/2021	Piperine Targets Different Drug Resistance Mechanisms in Human Ovarian Cancer Cell Lines Leading to Increased Sensitivity to Cytotoxic Drugs.
4/2019	PTPRK Expression Is Downregulated in Drug Resistant Ovarian Cancer Cell Lines, and Especially in ALDH1A1 Positive CSCs-Like Populations.
9/2018	The Role of Matrix Gla Protein (MGP) Expression in Paclitaxel and Topotecan Resistant Ovarian Cancer Cell Lines.
1/2018	Myotilin, a New Topotecan Resistant Protein in Ovarian Cancer Cell Lines.
10/2017	New and Old Genes Associated with Primary and Established Responses to Cisplatin and Topotecan Treatment in Ovarian Cancer Cell Lines.
9/2017	The significance of lumican expression in ovarian cancer drug-resistant cell lines.
7/2017	Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines.
1/2017	New and Old Genes Associated with Topotecan Resistance Development in Ovarian Cancer Cell Lines.

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Michał Nowicki Research Topics

Disease

27	Neoplasms (Cancer) 06/2022 - 01/2006
20	Ovarian Neoplasms (Ovarian Cancer) 06/2022 - 08/2013
14	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2021 - 02/2003
11	Chronic Kidney Failure (Chronic Renal Failure) 01/2021 - 04/2002
9	Proteinuria 11/2021 - 04/2003
8	Chronic Renal Insufficiency 04/2022 - 10/2013
6	Hypertension (High Blood Pressure) 11/2021 - 03/2006
5	Fabry Disease (Fabry's Disease) 11/2021 - 01/2020
4	Inflammation (Inflammations) 01/2022 - 04/2010
3	Infections 06/2022 - 01/2006
3	COVID-19 11/2021 - 01/2021
3	Circulating Neoplastic Cells 09/2021 - 06/2019
3	Xerostomia 10/2020 - 01/2009
3	Diarrhea 10/2016 - 05/2010
3	Atherosclerosis 01/2015 - 01/2011
3	Insulin Resistance 12/2013 - 01/2006
3	Weight Gain 09/2011 - 01/2009
3	Renal Insufficiency (Renal Failure) 12/2007 - 01/2002
3	Disease Progression 01/2006 - 02/2004
2	Albuminuria 12/2021 - 12/2013
2	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 11/2021 - 01/2006
2	Glomerulonephritis 11/2021 - 12/2002
2	Prostatic Neoplasms (Prostate Cancer) 09/2021 - 06/2019
2	Hypertriglyceridemia 05/2021 - 07/2012
2	Pain (Aches) 05/2021 - 03/2011
2	Anemia 05/2021 - 02/2018
2	Neoplasm Metastasis (Metastasis) 04/2020 - 04/2011
2	Breast Neoplasms (Breast Cancer) 05/2016 - 08/2015
2	Colorectal Neoplasms (Colorectal Cancer) 08/2015 - 04/2011
2	Vascular Calcification 01/2015 - 03/2010
2	Nephritis 04/2005 - 12/2002
2	Urolithiasis 07/2003 - 03/2003
2	Hyperkalemia 06/2002 - 01/2002
1	Endometriosis 06/2022
1	Infertility (Sterility) 06/2022
1	Hodgkin Disease (Hodgkin's Disease) 04/2022
1	Eosinophilia 04/2022
1	Acidosis 04/2022

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 06/2022 - 01/2006
16	Pharmaceutical PreparationsIBA 06/2022 - 10/2004
14	Topotecan (Hycamtin)FDA LinkGeneric 05/2022 - 01/2014
11	Paclitaxel (Taxol)FDA LinkGeneric 06/2022 - 01/2014
11	SteroidsIBA 01/2021 - 02/2003
10	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2022 - 01/2014
8	Cyclosporine (Ciclosporin)FDA LinkGeneric 11/2021 - 02/2003
6	Messenger RNA (mRNA)IBA 06/2022 - 08/2013
6	Cisplatin (Platino)FDA LinkGeneric 04/2019 - 01/2014
5	CreatinineIBA 11/2021 - 04/2005
5	Biomarkers (Surrogate Marker)IBA 11/2021 - 03/2010
4	LipidsIBA 10/2013 - 04/2010
3	Glucose (Dextrose)FDA LinkGeneric 12/2021 - 01/2006
3	Uric Acid (Urate)IBA 01/2021 - 04/2010
3	Methotrexate (Mexate)FDA LinkGeneric 08/2019 - 01/2016
3	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 07/2019 - 03/2003
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 07/2019 - 07/2012
3	Vincristine (Oncovin)FDA LinkGeneric 04/2019 - 01/2016
3	Tacrolimus (Prograf)FDA LinkGeneric 10/2013 - 05/2010
3	Antihypertensive Agents (Antihypertensives)IBA 01/2012 - 03/2006
3	Immunosuppressive Agents (Immunosuppressants)IBA 01/2006 - 10/2004
2	MicroRNAs (MicroRNA)IBA 05/2022 - 01/2021
2	GlucocorticoidsIBA 01/2022 - 11/2021
2	MineralsIBA 12/2021 - 11/2009
2	Phosphates (Orthophosphate)IBA 12/2021 - 12/2013
2	Antineoplastic Agents (Antineoplastics)IBA 09/2021 - 04/2021
2	Contrast MediaIBA 05/2021 - 04/2013
2	EnzymesIBA 04/2021 - 11/2017
2	Losartan (Cozaar)FDA LinkGeneric 01/2021 - 01/2009
2	FructoseIBA 01/2021 - 10/2013
2	CollagenIBA 12/2018 - 01/2016
2	Matrix Gla ProteinIBA 09/2018 - 01/2016
2	Cytostatic AgentsIBA 07/2017 - 01/2016
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 05/2016 - 07/2013
2	Vitamin K 2 (Vitamin K2)IBA 01/2016 - 01/2015
2	AlbuminsIBA 01/2016 - 01/2005
2	Subfamily B ATP Binding Cassette TransporterIBA 08/2015 - 08/2013
2	Glycoproteins (Glycoprotein)IBA 08/2015 - 01/2013
2	Vitamin D FDA LinkGeneric 01/2013 - 11/2009
2	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2012 - 10/2004
2	Everolimus FDA Link 10/2011 - 05/2010
2	C-Reactive ProteinIBA 05/2010 - 04/2010
2	Serum AlbuminIBA 05/2010 - 01/2008
2	ElectrolytesIBA 05/2010 - 01/2009
2	Insulin (Novolin)FDA Link 04/2010 - 01/2006
2	Blood Proteins (Serum Proteins)IBA 04/2005 - 04/2003
2	Adrenergic Agents (Adrenergic Drugs)IBA 06/2002 - 01/2002
1	Nuclear Proteins (Protein, Nuclear)IBA 06/2022
1	Interferon-gamma (Interferon, gamma)IBA 06/2022
1	Immunoglobulin E (IgE)IBA 04/2022
1	Bicarbonates (Hydrogen Carbonate)IBA 04/2022
1	Sodium Bicarbonate (Baking Soda)FDA LinkGeneric 04/2022

Therapy/Procedure

20	Therapeutics 04/2022 - 02/2003
12	Drug Therapy (Chemotherapy) 06/2022 - 04/2011
10	Renal Dialysis (Hemodialysis) 11/2017 - 01/2002
5	Kidney Transplantation 10/2019 - 03/2011
5	Peritoneal Dialysis 06/2007 - 04/2002
3	Transplantation 05/2021 - 01/2005
3	Enzyme Replacement Therapy 01/2021 - 01/2020
3	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2008 - 02/2003
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 10/2019 - 12/2012
1	Lymph Node Excision (Lymph Node Dissection) 04/2022